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October 2009

Volume 1 Issue 10

 

 

In This Issue

·         Do Stem Cell Treatments Work?

 

Heart Disease

Diabetes

Cerebral Palsy

Amputation

Stroke

Multiple Sclerosis

 

 

 

Don Margolis
Founder and Chairman
don@repairstemcells.com

 

www.repairstemcells.com
Bangkok, Thailand

 

In the next two newsletters we will answer two of the most important questions the prospective stem cell treatment recipient should be concerned with:

#1 DO STEM CELL TREATMENTS WORK?

#2 ARE STEM CELL TREATMENT BENEFITS MERELY A PLACEBO EFFECT?

 

 

Do not take one step further in your plans for treatment or read one more word about stem cells anywhere else until you believe that we have answered this question, unequivocally and without a shadow of a doubt:

 

 

DO STEM CELL TREATMENTS WORK?

 

Ask most US doctors if repair stem cell treatments work and they will tell you “NO!”  You may also get condescending retorts, misinformation and derisive abuse.  But if you press them on the question, eventually they will give you the reason why they believe repair stem cells don’t work.  The top answer WHY STEM CELLS DON’T WORK is… (Survey Says!):

 

There have been no clinical trials to date that prove they do work.

 

When all is said and done, in the end, there is nothing that will convince a western doctor of the effectiveness of stem cell treatments besides clinical trials.  So have there been any stem cell clinical trials? Is all of the evidence supporting the benefits of stem cell treatments anecdotal as virtually every western doctor says? NOT ON YOUR LIFE!  Have there been clinical trials?  The answer is a resounding “YES!” 

 

According to the National Institutes of Health, there were and are ~2600 stem cell clinical trials around the world - http://www.clinicaltrails.gov/

·         Of those ~2600 trials, there are only nine mentions of embryonic stem cells. 

·         Of those 9, there are no actual embryonic clinical trials.  

·         Of those ~2600, there are ~2591 mentions of adult stem cells.

·         Of those ~2591, about half of them (~1300) are actual adult stem cell clinical trials.

 

Let’s look at (only) a few of those ~1300 clinical trials:

 

 

HEART DISEASE CLINICAL TRIALS

 

via http://donrmargolis.com/Home/Blog/April-2009/A-Brief-History-of-Stem-Cells.aspx

  • 2002 - clinical trial led by Dr. Hans Dohmann plus six colleagues in Brazil took 21 transplant candidates and gave 14 of them bone marrow cells. The results were so spectacular that the American Heart Association accepted the paper and it was presented in 2003. Five of the seven in the control group opted in to make a total of 19 stem cell transplants. The mortality rate for transplant candidates is about 35% per year. At that rate there would be, of those 19, only 2.2 patients still alive without a transplant after five years. There were, in fact, 12 alive as of Dec. 31, 2007; more than five years down the road.
    • In 2002, if you did not want or could not get a heart transplant (as is true of 90%+ of dying heart patients in North America) then you had to make a choice between stem cell treatment or standard Western Cardiology methodology.

1.      Western Cardiology methodology in 2002 kept 12% of transplant-waiting-patients alive for five years. 

2.      Adult/repair Stem cell treatments in 2002 kept 63% of transplant-waiting-patients alive for five years.  More than 5 times more heart transplant candidates lived for 5 years with stem cell treatments than the typical heart transplant recipient!  Btw, stem cell science has made huge advancements in treating heart disease over the past seven years.

  • 2003 - Dr. Andreas Zeiher of the Goethe Institute in Frankfurt began much larger trials. As of 2007, he has overseen more ASC implants into hearts than anyone, both in and out of clinical trials and he was the first to prove that timely implant of RSC in new heart attack victims improves future mortality and morbidity - http://circ.ahajournals.org/cgi/search?journalcode=circulationaha&fulltext=zeiher
  • 2004 - Dr. Amit Patel of Pittsburgh completed two of the most successful trials ever.  In Uruguay, he proved, on a group of ischemic heart failure patients, that a bypass plus cells was infinitely better than a bypass only. That same year, TheraVitae, in Israel, developed a new, powerful blood-derived stem cell and dared to treat the sickest patients no clinical trial (except Brazil) would consider.
  • 2004 - One of the Brazilians, Dr. Perin, came to Texas, used the Brazil results to get the first ASC heart clinical trial approved by the FDA. Over a dozen such approvals were granted in the next 12-18 months.
  • Clinical trials at the Mayo Clinic in Florida have seen successes in reversing and curing pulmonary hypertension using adult stem cells from patients’ own blood.
  • A timeline of cardiac history/predictions: http://donrmargolis.com/Home/Blog/January-2008/DON-MARGOLIS-ADULT-STEM-CELL-CARDIOLOGY-QUOTES-200.aspx

 

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DIABETES CLINICAL TRIALS

 

  • FIRST USE OF CORD BLOOD TO ALTER COURSE OF TYPE 1 DIABETES, June 25, 2007 – (I’ll bet nobody heard of this one!)transfusion of stored, autologous (i.e. the person’s own), umbilical cord blood into a group of children newly diagnosed with type 1 diabetes appears to have reduced their disease severity, possibly re-setting the immune system and slowing the destruction of their insulin-producing cells, according to a report presented today at the American Diabetes Association's 67th Annual Scientific Sessions. –http://parentsguidecordblood.org/content/media/m_pdf/ADA_T1D_PR-06-25-07.pdf - (The ADA in 2007 knew stem cells can treat Diabetes type 1 in children!)
  • Diabetes type 1 stem cell clinical trial – Enrollment 11/2003-4/2008, follow-up until December 2008 - http://repairstemcell.wordpress.com/2009/09/14/type-1-diabetes-stem-cells-clinical-trial/
  • Why no diabetes clinical trial s in the US when mice were cured of diabetes type 1 in the 1990’s?  -  Weissman, a professor of pathology and developmental biology at Stanford University, states: “Stem cells are rare, self-renewing, and can regenerate body tissues.” He repeatedly expressed frustration that while many of his discoveries seemed to hold remarkable potential for life-saving treatments, commercial or regulatory hurdles have prevented his scientific research from benefiting human beings.  One example is, his mid-’90s research on type I diabetes, in which he demonstrated the ability to fully cure type I diabetes in mice using stem cells.  Even though the experiments avoided political controversy by using adult/repair stem cells, which do not come from embryos, Weissman ran into a road block when pharmaceutical companies refused to sponsor clinical trials. The therapy went nowhere. “The pharmaceutical companies had put profit over principle, preferring to keep diabetes sufferers dependent on costly insulin than to cure them once and for all.” - http://repairstemcell.wordpress.com/2009/09/13/research-from-90s-cures-type-1-diabetes/

 

CerebralPalsy

 

CEREBRAL PALSY CLINICAL TRIALS

 

 

 

 

AMPUTATION CLINICAL TRIAL

 

  • Bone Marrow Stem Cell Treatment Saves Legs - The results of a clinical trial to save volunteers’ leg from amputation by injecting (autologous bone marrow) stem cell concentrate to the limb affected by thrombo angitis obliterance (TAO) have been encouraging. The clinical trial is being conducted on patients suffering from blocks in the artery of the leg. Sixty patients enrolled, all of them were smokers. Some had diabetes.  “We have got very good results,”said Dr. K.S. Vijayaragavan, head of the Department of Vascular Surgery, Sri Ramachandra University, Chennai, who is conducting the trial. The legs of 89 per cent of the patients have been saved.”

 

 

stroke

 

STROKE CLINICAL TRIALS

 

  • “The stem cells had excellent safety profile. After carrying out Pet scans and MRIs thrice in a year on patients who received stem cells, we found no side effects. This study shows that stem cells are a safe and feasible therapy in acute stroke. http://repairstemcell.wordpress.com/2009/04/20/stem-cell-research-shows-adult-stem-cells-help-stroke-victims-adult-stem-cell-research/
  • The University of Texas, Health Science Center at Houston July 1, 2009       Several months after becoming the first patient in the United States to undergo a revolutionary new stroke treatment, Roland "Bud" Henrich continues to improve. Doctors intravenously injected Henrich, 61, with stem cells taken from his own bone marrow…"The stem cells, we believe, may help repair the damage to his brain caused by the stroke," said Sean Savitz, M.D., assistant professor of neurology at The University of Texas Medical School at Houston and the study’s lead investigator. "Animal studies have shown that when you administer stem cells after stroke, the cells enhance the healing. We know that stem cells have some kind of guidance system and migrate to the area of injury. They’re not making new brain cells but they may be enhancing the repair processes and reducing inflammatory damage." http://www.texmedctr.tmc.edu/root/en/TMCServices/News/2009/07-01/Stem+Cells+Tested+for+Treatment+of+Stroke.htm

 

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MULTIPLE SCLEROSIS CLINICAL TRIALS

 

  • Hematopoietic stem cell transplantation for multiple sclerosis – 2002 clinical trial based on data collected from TWENTY medical institutes around the world.  Conclusion: Autologous HSCT suggest positive early results in the management of progressive MS and is feasible – http://www.springerlink.com/content/1b19ldgyecqvny3w/
  • Autologous Stem Cell Transplantation in Progressive Multiple Sclerosis, Sep 16, 1999  These results appear better than those achieved by any other treatment of progressive multiple sclerosis, including beta-interferon… - http://www.springerlink.com/index/H6X0866N90633266.pdf
  • "Dose of stem cells reverses some MS" - January 31, 2009 – STUDY - "A dose of their own stem cells "reset" the malfunctioning immune system of patients with early-stage multiple sclerosis and, for the first time, reversed their disability, according to researchers at Northwestern University in Chicago. Three years after being treated, on average, 17 of the 21 patients had improved on tests, suffering fewer problems with their balance or vision, 16 had experienced no relapse, and none had deteriorated.  This marks the first “reversal" of neurologic loss caused by this disease, says Richard Burt of Northwestern University in Chicago.

 

What is clear is that the overwhelming majority of Repair Stem Cell vs Disease clinical trials have been successful. 

·         The majority of patients treated with stem cells get better. 

Not all, but the majority.

·         The majority of patients treated with stem cells get better. 

Not cured, but better.

 

No western doctor in the world can come to matching the statistical success of stem cell treatments with pill-based “cures” for diseases that they define as “untreatable” and “incurable.”

 

WHAT HAVE WE LEARNED?

 

What have we learned?

 

  • Now you know there are 1300 real adult/repair stem cell clinical trials.
  • Now you know that adult/repair stem cell treatments work on most patients.
  • Now you know that while the disease is not cured, their condition does improve considerably.
  • Now you know that stem cell treatments are a significantly better choice than pill after pill after pill.
  • Now you know that stem cell treatments can provide more benefit to patients with so-called “incurable” diseases like Diabetes, Heart Disease, Stroke, Multiple Sclerosis and Cerebral Palsy. 

 

Based upon this information, can you now answer the question DO STEM CELL TREATMENTS WORK?

 

OF COURSE YOU CAN!

 

Based upon this information, can you now answer the question DO STEM CELL TREATMENTS WORK unequivocally and without a shadow of a doubt?

 

OF COURSE YOU CAN!

 

Well do they?

 

OF COURSE THEY DO!

 

 

Green light!

 

Green light means go!  You may now take the next step in your plans for treatment! If you have any questions at all about stem cell treatments, clinical trials or the information you’ve seen here, please do not hesitate to contact the Repair Stem Cell Institute: http://repairstemcells.com or don@repairstemcells.com


Stem Cell Treatment NOW!

Considering Stem Cell treatment for a loved one?
The Repair Stem Cell Institute will help you find the right doctor!
Click here to fill out a treatment request form... No charge for this service.

 

 

Stay tuned!  In the next newsletter we will tackle the second of the two most important questions that the prospective stem cell treatment recipient should be concerned with:

 

#2 ARE STEM CELL TREATMENT BENEFITS MERELY A PLACEBO EFFECT?

 

 

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Super Stemmys, Doris and the Supercells is the first ever children’s story on stem cells. 

A stem cell named Doris and her stem cell friends must all join forces and work together to repair an ailing heart and defeat Morbidus the Vile.

 

100% of the proceeds from sales of

Super Stemmys, Doris and the Supercells

go to the Repair Stem Cell Institute (RSCI) to help patients.

 

RSCI is the only public service institute in the world dedicated to help patients connect with the top 2% of the world’s stem cell treatment centers.  Patients looking to shed the debilitating symptoms of once-untreatable diseases no longer have to wait.

 

 

 

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Jump on board for a freewheeling ride that will leave you armed and ready for those who call you an anti-science clod for opposing destruction of human embryos for stem cell research. The NIH is about to release new guidelines on broader federal funding for embryonic stem cell research. That will touch off another round of false hype about “hope” and “cures” from embryo-destructive research.

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When the author became aware that 50% of all heart attacks had been happening  to people with so called,  normal cholesterol, he began a five year research and writing project to identify other hidden factors that were unsuspectedly destroying lives.

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Hearts - damaged from heart attack and heart failure, previously considered irreparable are now for the first time in medical history being renewed using the patient's own stem cells in a onetime procedure. FDA trial directors from 8 major universities explain the science. Patients share their personal journeys from near death to renewal literally in weeks. Before/after scans.

 

 

Contact

USA Direct Line:
Tel. +1­ 214 ­556 ­6377

Don Margolis, Chairman
The Repair Stem Cell Institute
PT Court
1 Rangnam Rd., Phayathai
Bangkok, 10400
Thailand

 

www.repairstemcells.com
The Voice of Stem Cell Science

www.donrmargolis.com
Don Margolis’ Personal Blog

LEGAL DISCLAIMER

This Newsletter is for educational purposes only and not to be taken as medical advice.

We provide the contact information; the doctors provide the medical advice.